About   Contact    |

Caine Powder Online

Benzocaine Powder | Procaine Powder | Lidocaine Powder and more




What is Procaine Powder

Procaine is a local anesthetic, and its hydrochloride is called novocaine. With its hydrochloride, it is white crystalline or crystalline powder. It is odorless and slightly bitter. A sense of paralysis follows. It is soluable in water. The duration of procaine’s local anesthesia is about 1 hour. If a trace of adrenaline is added to the drug solution, the effect can last for 1 ~ 2 hours. It has weak penetration to skin and mucous membrane, and it is not suitable for topical anesthesia. After absorption, the product is mainly hydrolyzed into p-aminobenzoic acid and diethylaminoethanol by plasma pseudocholinesterase. The former can competitively resist the antibacterial effect of sulfonamides and weaken the curative effect of sulfonamides; the latter can enhance the effect of digitalis. Patients who have used enough digitalis shall use this drug with caution. If procaine is combined with succinylcholine, both drugs are hydrolyzed by plasma pseudocholinesterase. When a large amount of procaine is injected intravenously, it may compete with hydrolase to reduce the hydrolysis and inactivation of succinylcholine, significantly strengthen and prolong its muscle relaxation, result in respiratory muscle paralysis. If a large amount of procaine is absorbed, it will stimulate the central nervous system, and then turn to inhibition, which is manifested as restlessness, convulsion, coma and respiratory paralysis. A few patients have allergic reactions.


Chemical Market Report 2022



    Procaine Powder Uses

    Injection: 40 mg/2 ml,100 mg/10 ml,50 mg/20 ml,100 mg/20 ml。 For infiltration anesthesia: 0.25% ~ 0.5% solution, 4% solution can be used in stomatology department, which may not exceed 1g at a time. For conduction anesthesia:1% ~ 2% solution, no more than 1g at a time. For epidural anesthesia:2% solution, maximum 1 g. For subarachnoid block anesthesia: 3% ~ 5% solution, no more than 0.1g at a time.

    What is Procaine Used For

    It is applicable for infiltration anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia. It is also used for local sealing of peripheral nerves.

    Procaine Powder Effect

    This product is an ester local anesthetic, which can temporarily block the conduction of nerve fibers and has anesthetic effect. This product has weak penetration to skin and mucosa and it is not suitable for topical anesthesia. This product inhibits the central nervous system and excessive amount can cause excitation. First, it causes sedation, dizziness, increases pain threshold, and then causes dizziness, disorientation and ataxia. Central inhibition continues to deepen, resulting in slow perception and blurred consciousness, and then a coma state will be caused. If the dose continues to increase, there may be toxic symptoms of central excitement such as muscle tremor, irritability and convulsion. A small dose of this product can excite the sympathetic nerve, accelerate the heart rate, increase the blood pressure. If the dose increases, the blood pressure decreases and the heart rate increases due to myocardial inhibition, peripheral vasodilation and slight ganglion blocking. This product can inhibit the release of acetylcholine from presynaptic membrane, produce certain neuromuscular blockade, enhance the effect of competitive muscular relaxants, directly inhibit smooth muscle and relieve smooth muscle spasm.
    Leave a message